Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Short courses only, and not alongside psychiatric medication.
Who it's actually for
Discuss with a doctor first if you have any mood diagnosis.
Safe upper limit
UnverifiedNo formal limit; 50–300 mg daily in trials
Serotonin syndrome risk when stacked with serotonergic drugs. This can be fatal.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Antidepressants — SSRIs, SNRIs, MAOIs, tricyclics
- Sedatives / sleep medication — Benzodiazepines, zopiclone, zolpidem, opioids
- Tramadol — Serotonergic painkiller
- Triptans — Sumatriptan and similar migraine drugs
Other supplements:
Run your full list through the interaction check.
Practical notes
- Never combine with SSRIs, SNRIs, tramadol, triptans, or St John's wort.
- Stop before surgery.