Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Three to six month trial alongside glucosamine. If nothing changes, stop.
Who it's actually for
Knee osteoarthritis, with modest expectations.
Safe upper limit
UnverifiedNo formal limit; 800–1,200 mg daily is standard
Well tolerated. The main caution is a possible effect on blood clotting.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Blood thinners / antiplatelets — Warfarin, apixaban, rivaroxaban, clopidogrel, aspirin
Other supplements:
Run your full list through the interaction check.
Practical notes
- Usually derived from bovine or shark cartilage — check the source if that matters to you.
- Trial results are inconsistent; the largest studies found little benefit over placebo.