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4Optional

Citrulline malate

Also sold as L-citrulline, watermelon extract

Blood flow and training volume support; better absorbed than arginine.

4TrustedSupp Tier System™ · Tier 4Take by choice, or not at all

How long to take it

Situational, before training.

Who it's actually for

People doing higher-volume resistance training.

Safe upper limit

Unverified
No formal limit; 6–8 g pre-workout in trials
Well tolerated. Stomach upset at high doses.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Blood pressure medication — Beta blockers, calcium channel blockers, ACE inhibitors
  • Nitrates — GTN spray, isosorbide

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Absorbs far better than arginine, which is largely destroyed in the gut.
  • Mildly lowers blood pressure — relevant if you already take BP medication.