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3Medicinal

DHM (Dihydromyricetin)

Also sold as Hovenia dulcis, japanese raisin tree, hangover supplement

Marketed for hangovers and alcohol metabolism. Popular, but the human evidence is thin.

3TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Occasional, situational use. There is no basis for taking it daily.

Who it's actually for

People looking to reduce hangover symptoms — with the caveat that the evidence is mostly animal studies.

Safe upper limit

Unverified
No formal limit; 300–600 mg is typical. Human safety data is limited
Short-term use appears well tolerated, but there is no long-term safety data and no established limit.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Liver disease or impairmentHepatitis, cirrhosis, fatty liver
  • Sedatives / sleep medicationBenzodiazepines, zopiclone, zolpidem, opioids

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Most of the supporting research is in rodents; human trials are few and small.
  • It does not reduce blood alcohol or make drinking safer — treating it as protection is the real risk here.
  • Interacts with anything else processed by the liver, including alcohol itself.