Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Not established. Course-based at most.
Who it's actually for
Limited justification outside specific clinical guidance.
Safe upper limit
UnverifiedNo formal limit; 100–200 mg daily is typical
Alters oestrogen metabolism and induces drug-clearing enzymes. Can cause headaches and darkened urine.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Hormonal contraception — Combined pill, mini pill, implant, hormonal IUD
- Hormone therapy — HRT, tamoxifen, testosterone, anti-androgens
- Any other prescription medicine — Catches broad enzyme and absorption effects
- Chemotherapy / cancer treatment — Any active oncology treatment
Run your full list through the interaction check.
Practical notes
- Can reduce the effectiveness of hormonal contraception.
- Cruciferous vegetables provide the precursor at food level.