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4Optional

Fisetin

Also sold as Senolytic flavonoid

A strawberry flavonoid promoted as a 'senolytic' that clears ageing cells — the idea comes from mouse studies; human outcome data barely exists yet.

TrustedSupp Tier System™ · Tier 4Take by choice, or not at all

Evidence strength

15/100Weak
WEAKLIMITEDMODERATESTRONGVERY STRONG

What the evidence supports: clearing senescent cells in animal studies; human outcome data is essentially absent.

This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.

How long to take it

Not established. No human evidence yet supports a specific protocol.

Who it's actually for

People comfortable experimenting ahead of the evidence — small clinical trials are underway but results are not in.

Safe upper limit

Unverified
No formal upper limit; high-dose 'pulse' protocols are extrapolated from animal work, not human trials
Short-term use appears well tolerated, but the high-dose pulsed protocols circulating online come from mouse research. Human safety data at those doses is thin, and absorption from standard capsules is poor.
No source or citation attached yet.

Interactions to know about

No commonly documented medication clashes in our data. That is not the same as none existing.

Run your full list through the interaction check.

Practical notes

  • 'Senolytic' effects have been shown in mice, not demonstrated as health outcomes in people.
  • Standard fisetin absorbs poorly; enhanced formulations exist but aren't proven better at outcomes.
  • Flavonoids at high doses can affect how some drugs are metabolised — mention it to a pharmacist if you take prescription medication.