← Back
1Essential

Fish oil (Omega-3)

Also sold as EPA, DHA, fish oil, omega 3

Requires oily fish two to three times weekly, which most diets never reach.

1TrustedSupp Tier System™ · Tier 1Take persistently
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Ongoing unless you genuinely eat oily fish several times a week.

Who it's actually for

Nearly everyone on a Western diet; particularly relevant for triglycerides and cardiovascular risk.

Safe upper limit

Unverified
About 3 g combined EPA+DHA per day from supplements
Higher intakes thin the blood measurably and can raise LDL in some people. Very high doses have been linked to atrial fibrillation. No single authoritative UL exists — agencies differ (FDA GRAS vs EFSA vs Health Canada). Needs a dedicated comparison before the site states one number with confidence.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Blood thinners / antiplatelets — Warfarin, apixaban, rivaroxaban, clopidogrel, aspirin
  • Blood pressure medication — Beta blockers, calcium channel blockers, ACE inhibitors

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Read the EPA/DHA numbers on the back, not the '1000mg fish oil' on the front.
  • Freeze the capsules to reduce fishy burps.
  • Discontinue before surgery on your surgeon's advice.