Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Three to six month trial. If nothing changes, stop.
Who it's actually for
Knee osteoarthritis, with modest expectations.
Safe upper limit
UnverifiedNo formal limit; 1,500 mg daily is standard
Can mildly raise blood sugar and has been linked to increased INR on warfarin.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Blood thinners / antiplatelets — Warfarin, apixaban, rivaroxaban, clopidogrel, aspirin
- Diabetes medication — Metformin, insulin, gliclazide, SGLT2 inhibitors
Other supplements:
Run your full list through the interaction check.
Practical notes
- Sulfate form has more supporting evidence than HCl.
- Usually shellfish-derived — check if you have an allergy.