Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Short courses only, with medical oversight.
Who it's actually for
Not a casual nootropic. Discuss with a doctor.
Safe upper limit
UnverifiedNo formal limit; 50–200 mcg daily. Treat as a drug
Genuinely drug-like. Can cause slow heart rate, nausea, and cholinergic side effects, and stacks dangerously with dementia medication.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Anti-seizure medication — Phenytoin, valproate, carbamazepine, lamotrigine
- Sedatives / sleep medication — Benzodiazepines, zopiclone, zolpidem, opioids
- Blood pressure medication — Beta blockers, calcium channel blockers, ACE inhibitors
- Any other prescription medicine — Catches broad enzyme and absorption effects
Other supplements:
Run your full list through the interaction check.
Practical notes
- Never combine with donepezil or similar dementia drugs.
- Avoid with slow heart rate, asthma, or epilepsy.