Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Course-based. Ongoing use without a liver condition has no clear rationale.
Who it's actually for
People with liver conditions, under medical supervision.
Safe upper limit
UnverifiedNo formal limit; 200–400 mg silymarin daily in trials
Generally well tolerated. Can mildly affect drug-clearing enzymes.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Any other prescription medicine — Catches broad enzyme and absorption effects
- Diabetes medication — Metformin, insulin, gliclazide, SGLT2 inhibitors
- Hormonal contraception — Combined pill, mini pill, implant, hormonal IUD
Other supplements:
Run your full list through the interaction check.
Practical notes
- Not a licence to drink more.
- Ragweed allergy sufferers may react.