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3Medicinal

Panax ginseng

Also sold as Korean ginseng, red ginseng

Used for fatigue and cognitive performance. Interacts widely.

3TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Courses of a few weeks with breaks; continuous use is not well studied.

Who it's actually for

Short-term fatigue and cognitive support.

Safe upper limit

Unverified
No formal limit; courses of 200–400 mg extract are typical
Can raise blood pressure, cause insomnia, and interact with several drug classes.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Blood thinners / antiplateletsWarfarin, apixaban, rivaroxaban, clopidogrel, aspirin
  • Diabetes medicationMetformin, insulin, gliclazide, SGLT2 inhibitors
  • Blood pressure medicationBeta blockers, calcium channel blockers, ACE inhibitors
  • AntidepressantsSSRIs, SNRIs, MAOIs, tricyclics
  • ImmunosuppressantsCiclosporin, tacrolimus, azathioprine, biologics, steroids

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Take in the morning.
  • Avoid with uncontrolled high blood pressure.