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3Medicinal

Passionflower

Also sold as Passiflora incarnata

Mild anxiolytic and sleep aid used short-term.

3TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Short courses of two to four weeks.

Who it's actually for

Mild situational anxiety or difficulty settling at night.

Safe upper limit

Unverified
No formal limit; commonly taken as tea or 250–500 mg extract
Additive sedation is the main concern, particularly with alcohol or sleep medication.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Sedatives / sleep medicationBenzodiazepines, zopiclone, zolpidem, opioids
  • Blood thinners / antiplateletsWarfarin, apixaban, rivaroxaban, clopidogrel, aspirin
  • Blood pressure medicationBeta blockers, calcium channel blockers, ACE inhibitors

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Don't combine with alcohol or benzodiazepines.
  • Avoid in pregnancy.
  • Stop before surgery — it adds to anaesthetic sedation.