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3Medicinal

Red yeast rice

Also sold as Monacolin K, RYR

Chemically a low-dose statin. The same monitoring applies.

3TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Ongoing only with lipid and liver monitoring, exactly as with a prescribed statin.

Who it's actually for

People managing cholesterol who should be having this conversation with a doctor.

Safe upper limit

Unverified
Monacolin K content is capped at 3 mg per day in the EU
It is a statin by another name — muscle damage, liver stress, and every statin interaction apply. Product potency also varies wildly between brands.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • StatinsAtorvastatin, simvastatin, rosuvastatin
  • Blood thinners / antiplateletsWarfarin, apixaban, rivaroxaban, clopidogrel, aspirin
  • ImmunosuppressantsCiclosporin, tacrolimus, azathioprine, biologics, steroids
  • Liver disease or impairmentHepatitis, cirrhosis, fatty liver

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Never combine with a prescription statin.
  • Get liver enzymes checked.
  • Contamination with citrinin, a kidney toxin, has been found in unregulated products.