Plant compounds with weak oestrogen-like activity, studied for hot flushes and bone health — modest benefits in some trials.
TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
Evidence strength
40/100Limited
WEAKLIMITEDMODERATESTRONGVERY STRONG
What the evidence supports: modest reduction in hot flush frequency in meta-analyses.
This scores how well-supported the claim above is — not how much benefit you personally would get. A high score on a narrow claim does not extend to everything the product is marketed for.
How long to take it
Course-based, reassessed after 3–6 months.
Who it's actually for
Women with menopausal hot flushes seeking non-hormonal options, after discussion with a clinician.
Safe upper limit
Unverified
No formal upper limit; 40–100 mg isoflavones daily in most trials
Food-level soy intake is considered safe. Concentrated supplements warrant more caution with hormone-sensitive conditions. Taken at the same time, soy can reduce absorption of thyroid medication.