Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.
How long to take it
Not established. Often taken ongoing without clear justification.
Who it's actually for
Vegans and people with specific cardiac or metabolic conditions.
Safe upper limit
UnverifiedNo formal limit; 1–3 g daily in trials
Well tolerated in studies up to 3 g daily.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.
Interactions to know about
- Blood pressure medication — Beta blockers, calcium channel blockers, ACE inhibitors
- Lithium — Mood stabiliser — narrow safety window
Other supplements:
Run your full list through the interaction check.
Practical notes
- Energy drinks contain it, but the caffeine is doing the work you notice.
- Recent ageing research is interesting but preliminary.