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1Essential

Vitamin K2

Also sold as MK-7, MK-4, menaquinone

Directs calcium into bone rather than arteries. Sparse outside natto and aged cheese.

1TrustedSupp Tier System™ · Tier 1Take persistently
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Ongoing alongside vitamin D, since the dietary sources are genuinely rare in most diets.

Who it's actually for

Anyone supplementing vitamin D long-term, and people managing bone density.

Safe upper limit

Unverified
None established
No formal upper limit, but the warfarin interaction is the hard constraint, not toxicity. No EFSA/NIH UL exists for vitamin K generally, but this needs direct confirmation. The warfarin interaction is the more load-bearing fact here and needs its own check.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Blood thinners / antiplateletsWarfarin, apixaban, rivaroxaban, clopidogrel, aspirin

Other supplements:

Run your full list through the interaction check.

Practical notes

  • MK-7 stays in the blood far longer than MK-4 — once daily is enough.
  • Take with fat.
  • If you are on warfarin, do not start or stop this without telling your prescriber.