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3Medicinal

White willow bark

Also sold as Salicin

Aspirin-like action — the same bleeding and stomach cautions apply.

3TrustedSupp Tier System™ · Tier 3Take as a defined course
Check before you startThis one has documented interactions with medication classes where the consequences are serious. If you take any prescription medicine, run it past a pharmacist before starting.

How long to take it

Short courses for pain flares.

Who it's actually for

Adults with musculoskeletal pain who tolerate aspirin.

Safe upper limit

Unverified
Treat as you would aspirin; 120–240 mg salicin daily in trials
It is chemically close to aspirin. Bleeding risk, stomach irritation, and Reye's syndrome risk in children are all real.
No source attached yet. Treat this as a starting point, not a citation, until reviewed.

Interactions to know about

  • Blood thinners / antiplateletsWarfarin, apixaban, rivaroxaban, clopidogrel, aspirin
  • Anti-inflammatories (NSAIDs)Ibuprofen, naproxen, diclofenac

Other supplements:

Run your full list through the interaction check.

Practical notes

  • Do not give to children or teenagers.
  • Avoid entirely if you are on an anticoagulant or have aspirin allergy.